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Comment Reading each other's code? (Score 2) 263

Lots of comments about being unable to read code authored by someone else (as usual), but who are these "professional perl coders"? I'd say I'm an intermediate perl programmer, and I've had no trouble reading my old code or anyone else's provided it's been written sensibly. Hell I've even been able to decipher some pretty Byzantine code when required.

Perl isn't a language without faults, for example OO is not fun in perl. However, it mystifies me to see perl criticised for readability when the coder is, in no small part, responsible for making something decipherable. I've seen shocking code in several languages, where I work I know there's a particularly hairy example of cold fusion we're still struggling to tame... Diabolical use of in-line HTML, thousands of lines of code without so much as an attempt at basic formatting (no indents) etc, etc. It was written by a genius I'm told, but why they deserve that title when they weren't smart enough to write something we could maintain I'll never know.

Comment Re:good (Score 1) 783

The trouble with evolution is that is it's so fundamental to the subject you can't avoid mentioning it at some point in a biology class. If you can't dodge the subject (which is counter productive anyway) then it has to be addressed factually. I don't see the problem here really, it's just reiterating what should happen anyway i.e. a lesson should accurately reflect it's subject matter. As an aside, ranking "what's more important" is terribly subjective, especially cross discipline. Where do you stop? Should we teach poetry? it's clearly less important etc. etc.

Comment Re:Not a "single gene" (Score 1) 243

Agreed, I'm definitely not a fan of calling miRNA genes (even in a genomic context). I've seen a few people refer to RNA genes or non-coding RNA genes, but the nomenclature is still somewhat in flux. Whatever the case, use of the word "gene" without a qualifier definitely implies a protein product IMPO, which is a bit sloppy.

Comment Not even close to accurate head line (Score 1) 243

The actual paper is here: http://www.nature.com/ncomms/journal/v3/n10/full/ncomms2146.html It's talking about miRNA *not* genes, nor does the paper claim or support the notion this is the single defining difference between humans and apes. For those who don't know, not all of our RNA encodes cellular machinery. Some RNA molecules regulate whether other RNA molecules go on to make a functional protein, this paper is describing a class of regulatory RNA that may act on many hundreds of targets. (To quote from the Discussion: "birth of a novel miRNA might influence expression of hundreds of genes"). In this instance, some of the targets regulated by this new miRNA are neural so it appears to be a very significant finding. It's a very interesting paper, utterly over-egged by the headlines. I suspect a dodgy press release/over excited journalists.

Comment Re:Sewage (Score 1) 179

I'd like to add another question if I may:

7. How many areas of resource usage can be improved by genetic engineering?

We've barely got started on the best way to make biofuels, there are an awful lot of powerful tools at our disposal.

Comment Venter is fond of sensationalism (Score 1) 142

Here we go again, Venter is less of a scientist more of a salesman and self publicist. Take a vaguely interesting idea and throw in a good dose of hyperbole and voila instant headline. Mention Mars and recreating life from there and the news outlets slavishly snap it up no matter how stupid the idea is... Honestly, there's very little of interest to see here, not least because we're not even sure there's life to find and sequence yet. Tiresome.

Comment Re:Because GNOME is too stupid and KDE is too slow (Score 1) 818

Yeah I've noticed the KDE slow down too, I briefly switched from GNOME recently as I just couldn't deal with the GNOME 3 training wheels set up. Now I'm in a kind of desktop limbo, I'm warming to GNOME again for it's minimalist looks but slowly moving towards XFCE and LXDE as the more lightweight alternatives... Back to the topic in hand though, as stated above Linus most certainly isn't championing a switch from GNOME to another desktop.
Science

Submission + - Biologists create synthetic DNA capable of EVOLUTION (theregister.co.uk)

Norwell Bob writes: Synthetic DNA and RNA has been shown to be capable of evolving in the lab, carrying hereditary traits with it.

The synthetic form of DNA, life's building block, was able to share information with real DNA and undergo directed evolution into biologically useful forms.

Boffins are studying the fundamental question about DNA: where did it come from?

Biotech

Submission + - Artificial DNA replicates and 'evolves' (nature.com)

ananyo writes: Scientists have demonstrated that several lab-made variants of DNA can store and transmit information much like the genuine article.
DNA is made up of nucleic acid bases — labelled A, C, G and T — on a backbone made of phosphates and the sugar deoxyribose. The artificial polymers, dubbed XNAs, carry the normal genetic 'alphabet' on a backbone made using different sugars.
The researchers engineered enzymes that transcribed DNA into the various XNAs, then back into new DNA strands. Faithful genetic transmission over successive DNA-to-XNA cycles allowed researchers to select for only those XNAs that attached to certain target proteins from a pool of random samples — a process akin to evolution over multiple generations (abstract).
The research confirms for the first time that replication, heredity and evolution can take place in artificial DNA-like molecules.

Comment Re:This makes perfect sense (Score 3, Interesting) 293

Exactly, what the study is highlighting is that the vaccine's efficacy may wane slightly earlier than expected which means the booster at 12 years of age is a bit too late to provide continuous protection. At worst the study is pointing to the need for additional/rescheduled vaccinations, not that the vaccine is ineffective. Moreover the article notes: "Ward, who did not participate in the new study, also said that immunized kids who catch whooping cough don't get as sick as unimmunized kids." If anyone has ever seen whooping cough in action you'll know how important reducing the symptoms is...

Submission + - Better Batteries through Simulation (utexas.edu)

aarondubrow writes: "In their paper, Ceder and his team describe the creation of Li9M3(P2O7)3(PO4)2 or lithium pyrophosphate — a material that never existed before — by means of artificial intelligence calculations performed on local clusters at MIT. They then turned to the Ranger supercomputer at TACC to perform diffusion calculations on the new material. The simulations led the scientists to understand why the material worked better than its less-complex relatives, and how it can be improved further."

Submission + - Immunized Children More Likely to Contract Whooping Cough says California Study (reuters.com) 1

An anonymous reader writes: In early 2010, a spike in cases appeared at Kaiser Permanente in San Rafael, and it was soon determined to be an outbreak of whooping cough — the largest seen in California in more than 50 years.

Witt had expected to see the illnesses center around unvaccinated kids, knowing they are more vulnerable to the disease.

"We started dissecting the data. What was very surprising was the majority of cases were in fully vaccinated children. That's what started catching our attention," said Witt.

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