I happened to watch one of her videos last week, and I do share the opinion of the first +5 poster: "her videos are, in places, poorly researched with many leaps of logic mixed with heavy opinions. But, they still contain very valid points and can be civilly debated."
Specifically, and though she clearly does make some points about the way most female NPC are limited to eye candy, her general attitude towards sandbox games reminded me heavily of the Dungeon&Dragons-bashing of the early 80's: "Can you imagine that? In this foul game players can invoke demons! What would be a better proof that it's a satanic plot to enroll our younglings in the Army of Darkness?" without, of course, ever explaining to the alarmed parents that a RPG allows player to do anything they can think of, and that if they don't have a particular interest in the evocation of demons there is no reason for them to do it (BTW at least in AD&D first edition I don' think there even is a rule about demonic invocations)...
In Sarkeesian's videos, it translates as "Female NPC have no agency": Well, they're NPCs - maybe she should figure what the word means. And yes, female NPC are often not treated in the same way than male NPC and when she explains that she has valid points - but it's maybe 10% of her discourse, 90% being "women are NPCs in video games, oh the humanity!".
She even goes as far as saying that no woman NPC is depicted having her own agenda and personality - hellooo, ever heard of Sarah Kerrigan? I'm still in love with her as are probably half of all male geeks ever born, and we have only seen her face!
Similarly, one of her points is that in Sandbox games the hero is allowed to kill female NPCs: does she even understand the concept of a sandbox game?
Or when RedDeadRedemption makes fun of the Pulp trope of rescuing a lady bound on the railway, she uses it as a proof of how vilely misogynistic the game world is, without even acknowledging the parodic intention.