Comment Re:Why is this news? (Score 2, Informative) 196
I agree that we've always suspected that transcription isn't a high fidelity process. In fact, there is evidence that leads us to this conclusion (ex. the lack of a 'spell-checker' mechanism). However, just because we have evidence that points to an effect doesn't mean that it shouldn't be tested. The thing is, we've been surprised before. We've had evidence of other phenomena/behaviour should exist but when actually tested, it turned out that it was not as expected. For example, in the past it was thought that during ischemic events it was the lack of oxygen and nutrients that did the most damage, now it is known that reperfusion and the immune response subsequent to ischemic injury has a significant role in the damage done. As pointless as some of these experiments must seem, they still have to be run to test the conclusions of those other 'bloody' papers that the geneticists are reading.
On a side note, the genetic code is built in such a way that small errors here and there during the transcription process may not have a huge effect (64 codons represent ~20 amino acids plus a few stop codons).