The neutrinos from a core collapse supernova would be lethal to humans at the distance of Jupiter. Any given neutrino has very little chance of hitting interacting with normal density matter it passes through, but there are a LOT of neutrinos: about 0.05 solar masses of them.
Furthermore, they are the first things that escape from the core (apart from gravitational waves) since they move at near-lightspeed and have very little chance of interacting with the envelope of the star. The big flashy special effects are driven by the shockwave from the core reaching the surface, and that takes hours. So if you were at the distance of Jupiter, you would have time to die from neutrino effects before the blast hit you.
Admittedly, Betelgeuse is somewhat further away than Jupiter, and the only neutrino effects are likely to be a lot of very excited astrophysicists. But both Jupiter and Betelgeuse are much closer than 99.9999999999999999999% of the Universe, and much further away than everyone you've ever met, so the distance scales aren't that different.