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Submission + - Facebook faces a potential lawsuit for misleading the investors during its IPO (securityresearch.in)

akm1489 writes: "As a result of the current Security Policy or Implementation, Facebook has been notified with a responsible disclosure well in advance but has not replied.Facebook has claimed 845 million MAUs as of December 31, 2011 and 483 million daily active users (DAUs) on average in December 2011 in its filing with the SEC.So this number includes the number of real people accounts, multiple accounts, ghost accounts, virtual people, game accounts and such. Hence this becomes a breach of trust where the management has willfully misled the investors regarding its user penetration, revenue generation on ad policy. This issue led facebook to be notified with a responsible disclosure and may led to potential lawsuit."
Biotech

Gold Nanoparticles Help Red Blood Cells Deliver Drugs 36

New submitter MTorrice writes "Scientists decorated red blood cells with gold nanoparticles so they could trigger the cells to dump their contents with a zap from a laser. The laser pulses heated the particles to produce nanopores in the cells' membranes. The cells contained two fluorescent dyes and both flooded through the pores and out of the cells after the laser pulses. Although the researchers studied the release of dyes, their end goal is to use red blood cells as a vehicle for drug delivery, because the cells are naturally compatible with the immune system and circulate for days in the body. Until now, researchers have found easy ways to load the cells with drugs, but the challenge has been to control the molecules' release."
Facebook

Submission + - Is Facebook IPO a scam? (securityresearch.in)

akm1489 writes: "When we last looked at the big datacenters that these top .com companies run, Facebook had 800,000 computers, Google had 600,000 and Microsoft just 350,000. Facebook is just a one trick pony – that just does one thing beautifully – that is Social Networking. Google does that and also so many other things such as search, email, maps and so on. Microsoft even provides virtual labs where huge communities of developers get trained to use its technologies for free. And yet all these companies need fewer computers than Facebook – which means the costs for Facebook are much higher. Facebook attributes it to the higher level of engagement of its users – but does that higher level of engagement proportionally add to its revenue? Judge by yourself weather facebook IPO is scam or not."

Submission + - A wheelchair - Historical note (wheelchairrampguide.org)

Anonymous Coward writes: "As a means of transportation for people unable to move, the wheelchair was first mentioned in China. These are ancient Chinese manuscripts dated by 6 A.D., where pictures of wheeled chairs can be seen.
1595 is considered to begin the next stage of wheelchair historical development. A special luxury wheelchair equipped with footrests and armrests was made for the king of Spain Fillip II. The wheelchair resembled more a high pushcart and needed an invalid tender escort. In 1655 the British Stephen Farfler, a handicapped watchmaker, invented a three-wheeled vehicle which made it possible for him to move by himself. It was the first self-propelled and lever-driven wheelchair. By the 19th century self-propelled wheelchairs had been replaced with manual wheelchairs — a handicapped person pushed large back wheels by hands and thus drove the wheelchair. It was notably uncomfortable to move down the street in such wheelchair, because hands got very dirty. In 1881 an outer rim of minor diameter was added to the construction of the wheelchair. This rim was adjusted to the wheel. When pushing an outer rim a handicapped person needn't touch a wheel and in such a way the problem of "dirty hands" was solved.
It should be mentioned, wheelchairs of those times were rather bulky and it made difficult to keep and transport them. However, in 1933 an engineer Harry Jennings wanted to help his friend Herbert Everest and made the first portable wheelchair of light steel. It didn't take long to realize commercial opportunities of the invention and friends set up the company "Everest-Jennings" dealing with mass production of wheelchairs. This company was monopolizing the invalid care equipment market for many years.
Electric wheelchair was invented after WW2 by George Johann Klein,a Canadian inventor, for the injured war veterans. Electric wheelchair is considered to be one of Canada's greatest inventions."

Android

Submission + - Android web browser can not upload files (google.com)

MichaelSmith writes: I have an android phone and wrote a photo blogging application so that I could upload pictures directly from the phone. When I finally got around to testing from the browser on android the <input type=file> tag turned into a message Uploads Disabled. So I googled around and found this hilarious bug report which unfortunately confirms that Android can not upload files.
Biotech

Submission + - Making sense of the Alzheimer's drug pipeline (fiercebiotechresearch.com)

hlovy writes: Alzheimer's disease is a thief. It robs seniors of a lifetime of experience and memories as it also robs their children and other loves ones of the benefits of their wisdom. It empties the wallets of families, and leaves many emotionally drained at seeing their elders slowly disappear into themselves.

So, what new answers has medical science has come up with? At best, it's good news and bad news. First, the bad news: there is no cure. There is not even complete agreement as to its cause. There is a general consensus that extracellular amyloid-beta (Aß) plaques and intraneuronal tangles in the brain are to blame. Drugs being developed tend to target these plaques. But, at best, they hold off symptoms temporarily.

Now, the good news. Biomarkers research is making it increasingly possible to determine whether a person might develop Alzheimer's disease, perhaps even decades in advance. The earlier the disease is detected, the better the chances are of being able to delay its symptoms or at least prepare for them. It could be argued, however, that this detection capability is, in itself, a good news/bad news scenario.

But, those sticky philosophical issues aside, medical progress marches on in its usual lurching way--many failures mixed with some progress. Here's a rundown of what's on the market, recent drug failures, pipeline prospects and the most recent research from the the laboratory trenches.

Iphone

Submission + - Follows App Tracks Your Online Popularity (apple.com)

Anonymous Coward writes: "Follows lets you track your online popularity. Use this app to chart how many followers, friends, likes, subscriptions, connections or views you've accumulated across various social networks and services.

You can provide a custom URL to follows and have it track private data such as newsletter subscribers, comment counts, visitors, etc."

Submission + - KVM over IP: Eliminates the Distance Limitation As (smartvm.com)

peterdisuja writes: "One or more computers can be controlled with a single set of peripherals using an IP KVM Switch. However, the key feature of this device is that it bypasses the control limits of a typical switch by allowing users to remotely exercise control over IP with 128 bit browser based access. There is no need for a physical connection in the form of wires. This device gives the freedom to access the systems over a local area network or a wide area network from remote locations. Compatible with almost every operating system and network device in the office environment, these switches add a greater flexibility to the network by placing the systems where they are required and the peripherals where they are desired."
Bug

Submission + - Adobe Confirms Flash Bug, To Release Fix Next Week (ibtimes.com)

iamrmani writes: "Adobe is planning to release the fix for a "critical" vulnerability that affected certain versions of its flash player during the week of March 21, 2011.

Adobe rated the bug as "critical," which, if exploited would allow malicious native-code to execute, potentially without a user being aware. In other words, the bug could cause a crash and potentially allow an attacker to take control of the affected system.

Read more: http://www.ibtimes.com/articles/122830/20110315/adobe-flash-flash-player-bug-zero-day-bug-patch-vulnerability-excel-authplay-microsoft-adobe-reader.htm#ixzz1GfTnuinb"

Media

Submission + - Microsoft Calls Time on Zune Player (thinq.co.uk)

Stoobalou writes: Microsoft has hinted that its Zune Player hardware has reached the end of the road and that no further devices would be developed or released.

The Redmond software giant's feeble forays into the media player market always faced an uphill struggle in the face of Apple's utter dominance, the various flavours of its iPod hardware hogging as much as 77 per cent of sales in recent years, but that didn't stop Microsoft from pouring hundreds of millions of dollars into a string of devices which almost universally failed to gain favour with either reviewers or the gadget-buying public.

Apple

Submission + - Apple's Role in Japan during the Tohoku Earthquake (kevinrose.com)

TiZon writes: "As you all must have heard, the 5th largest earthquake in recorded history hit us on Friday, 2:30pm Japan Time. As Alex often says on TWiM, stories on the ground are often quite different from the stories in the news, and there is a tech story that I'd really like to tell: the story of Apple Inc in Japan."

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