Comment sequence != expression (Score 1) 123
The use of terms for sequence data and expression data are not interchangeable. The U133 microarray is for RNA, yes RNA, expression data. RNA microarrays quantify the fold change difference in expression between different subjects. DNA microarrays identify polymorphisms or repeats or the like. While arrays like the U133 rely on sequence level data to create the array, this is not the same as saying that sequence-level data is contaminated. Bottom line, the fact that this is not the cover article for Nature|Genetics this month tells you a lot of the story. Unless you are some sort of conspiracy theorist, or want to get swept up in the usual slashdot "sky is falling" imperative.