Comment Re:Showing pain, not feeling pain (Score 1) 274
So, that sounds impressive, but at most you patch clamps neurons, not nerves, and the relationship between activity nociceptive neurons and perceived pain is complex. Even were you able to record the activity of all nociceptive sensory neurons responding to the stimulus, you could not from that predict how the pain would be experienced in the brain, where the experiencing part is actually happening. (Heck, right now I'm working with sea slugs, that don't have brains, but instead just a number of ganglia, and even in that system of vastly fewer parts we can't make that kind of prediction.)
The canonical use of the term patch clamp refers to pulled patches - where you remove a small piece of membrane from a neuron to examine the activity of one or a small number of ion channels in that patch. I suspect what you're thinking of is whole cell patch clamping* where you use similar electrodes to create a similar seal, but rather than pulling a patch away from the cell, you blow the patch and instead clamp the whole cell, measuring the change in voltage or current in the whole cell (the "clamp" bit refers to holding one steady while measuring the changes in the other).
* Which, to be fair, is a ton of fun. And whole cell patch clampers - which is what I learned first - often use the term patch clamp without modifiers, just to confuse things.