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Comment Misleading (Score 1) 18

I currently work with mass spectrometry to study differences in protein expression levels to understand cancer. By using the Orbitrap, we are able to study proteins in femtomolar levels and we are still far from detecting biomarkers. In deed, the field of proteomics recognizes that such is still an open chalenge, even when analyzing simple cell cultures instead of complex biofluids such as plasma. The field has become tired of published manuscripts of biomarkers that have proven wrong and are an artifact of overfiting statistical approaches. In this regard, it could be misleading to "advertise" and article as such before proving the claims on large populations.
Biotech

New Nanotech Helps Detect Early-Stage Cancer 18

CWmike writes "Stanford University researchers have used nanotechnology and magnetics to create a biosensor that they said should be able to detect cancer in its early stages. The sensor, which sits on a microchip, is 1,000 times more sensitive than cancer detectors used clinically today, say scientists at Stanford. The researchers announced this week that the sensors have been effective in finding early-stage tumors in mice, giving them hope that it can be equally successful in detecting elusive cancers in humans. 'In the early stage [of a cancer], the protein biomarker level in blood is very, very low, so you need ultra-sensitive technology to detect it,' said Shan Wang, professor of materials science and engineering at Stanford. 'If you can detect it early, you can have early intervention and you have a much better chance to cure that person.' Wang also noted that the biosensor could be used to determine whether chemotherapy or other cancer treatments are working after only a few days."

Comment Mono in science (Score 1) 570

I currently research methods to improve cancer treatment using proteomics. Bioinformatics plays a key role. Thanks to Mono, we were able to port existing software to Linux and run in our cluster. Indeed, it must be recognized that Mono is contributing to this field and many others.

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