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Stalin thought to produce super-soldiers by producing these primate hybrids. In fact, Africans were involved in the experiment, because they were thought to be genetically more "compatible"(trailing behind the evolutionary timeline) .
This is the best google link I could find:
http://www.independent.co.uk/news/science/stalins-space-monkeys-808978.html
Actually, "We are made out of tubes" was one of the motivations mentioned in my friend's thesis presentation on fruit fly research. And it wasn't meant as a joke.
How about creating two portals near a gravitational object to accelarate and reach speed of light? No air means no terminal velocity. Unfortunately, it also means you're dead.
It's not the size of the brain that matters, but the surface area since the cortex is on the surface. Hence our convoluted brain.
waiting for a "size matters" joke...