No, as the series of court rulings have gone, the Fourth Amendment does not protect you from lawful search and seizure (such as a safe or hard drive). The combination to the safe, or encryption key to the drive, is not incriminating evidence and providing it to allow for lawful search and seizure does not violate your rights. They can admit evidence produced by oneself into court (such as two sets of books in one's own handwriting for a case of fraud) and that is not a violation of the Fourth (or Fifth) - just so with information one puts on a hard drive. What they can not compel one to do is testify against oneself (which is the Fifth by the way) nor assume guilt because you do not take the stand (not that a prosecutor won't toe that line with the jury). So, if one can keep all details of a crime in one's head and manage to destroy all other evidence which could be subject to lawful search and seizure - then you've got a shot at being a criminal mastermind.
I'm not sure I entirely agree with the line of thought - but I can certainly follow the logic as well as the precedence.
What would be interesting is if one's pass-code was material evidence with respect to the case - but a possible way around that would be limited immunity or ruling it as inadmissible evidence...It would make for an interesting case study.
Horse shit.
100 years from now Google Glass will be able to scan your brain and display your old memories for digital sharing, archival, and, of course, ad targeting.
Lawful search and seizure includes asking about your whereabout, whether you killed someone, etc., so using your logic, scanning your brain to find out where you were and what you were doing is just fine and dandy.
