Comment Re:Snake oil (Score 1) 213
As (another) analog designer who happens to be in the middle of designing a mixed-signal board, I can assure you that the right answer depends on how sensitive your analog circuitry is, and it could very well be that the answer is, "enough to drive you crazy trying to eliminate the interference."
Proper shielding of analog circuitry from digital interference, when the two are in close proximity, is really very, very hard. That's why you see all of the high-end audio cards have either (a) full faraday cages (plus careful PCB layout technique), or (b) are external to the computer case, or (c) both.
Five unshielded single-ended lines switching 1.8V at 208MHz that might not be properly terminated? Sounds like a powerful AM transmitter to me if my uV to mV level analog traces are anywhere near them.