How to make a website using modern tools?

Prolene writes: "Hello. I am trying to make website about the journal we are starting. The journal will be publishing latest researches regarding health and medicine. We cannot afford to hire professional services yet, so i have to come up with something. So far i have a domain name .com and officelive as my host. I am thinking about using a content management system to publish all the issues of the journal and index all the things in the articles. To achieve this i will be using: Client side scripting: Frontpage, Content management: Typo3. Is my approach correct? Will i be needing a database program as well? Any type of advise or suggestion or a comment will be very helpful. Thanks."