Slashdot is powered by your submissions, so send in your scoop

 



Forgot your password?
typodupeerror
×

Comment Re:Well then (Score 1) 294

This doesn't make any sense to me either. Current pills containing hydrocodone are a mixture with other drugs, mostly other drugs that have a higher toxicity, and part of the reason for that is to keep people from taking too many of them. If you OD on Vicodin, it's not the 5mg of hydrocodone that kills you, it's the 500mg of acetaminophen. For a 50kg person, you can get to a reasonably toxic quantity of acetaminophen (200 mg/kg) with 20 vicodin, which gives you a dose of 100mg of hydrocodone, or 2 mg/kg. Quick googling found this: http://toxnet.nlm.nih.gov/cgi-... that gives animal toxicity studies showing an LD50 for hydrocodone in the range of 86 mg/kg (mice) to 375 mg/kg (rats). Granted, you certainly don't want to take anything *near* to the LD50 of any drug, but the highest dosage for a Zohydro pill is 50 mg. For a 50kg person to get a dose of 1/4 the mouse LD50 would be over 20 pills. As noted, if those 20 pills were vicodin, then they would also be toxic, but only because of the acetaminophen. And really, if you're downing 20 of *any* prescription painkiller, you almost certainly have a different goal in mind than temporary pain relief. I just really don't see this as causing much harm, and potentially helping a fairly specific set of people who need it.

People who are intent on abusing pills can get around the acetaminophen simply by breaking the pills up, putting them in cold water, and running them through a coffee filter. This is known as cold water extraction.

Part of the reason for the acetaminophen in painkillers is because of a loophole in the 1970 Controlled Substances Act that classified pure Hydrocodone as a strictly controlled Schedule II drug (Which Zohydro will fall under). However, Hydrocodone combination products, such as Vicodin, which contains Hydrocodone and acetaminophen, into the less strict Schedule III classification. As a Schedule III drug, combination drugs such as Vicodin can be refilled as many as five times, while Schedule II drugs can be filled only once.

So why is there so much pushback against Zohydro, when it clearly fits a need and will be more difficult to obtain and abuse than Vicodin? I think it might have to do with the fact that it's put out by a tiny company (Zogenix) rather than one of the big players. Teva Pharmaceuticals who literally spent millions on lobbying last year has a competing product "TD Hydrocodone" which they're trying to get to market, but Zogenix beat them to it. If Zohydro were delayed for a little while, perhaps they could get to market with their competing drug and given their vastly larger resources they'd likely win market share. Another large company Purdue Pharma (the makers of OxyContin) also have something in the works

Comment Masters Of the Carrot and the Stick (Score 1) 253

They're doing a great job of maximizing revenue from a declining game. Instead of just coming out and offering everything on the store, they just offered pets and mounts at first. The implication was in game purchases would be limited to "Cosmetic items", and of course those willing to buy just cosmetic items did, since there were no functional items competing for their money.

Now they've crossed the Rubicon and will allow you to buy levels, as long as you buy the expansion. It's a good way to increase profits when you have a declining playerbase.

Comment Re:If that wasn't crueal and unreasonable... (Score 1) 1038

The phrasing in the 8th amendment is "cruel and unusual" FYI, and I'm pretty sure a court will find a stay of executions necessary until a new method is devised.

What is considered Cruel and Unusual changes over time.

A firing squad, beheading or hanging were considered just fine for a long time. Same goes for the Electric Chair, it was all the rage for decades. Now we're trying to put people to "sleep" with a comfy pillow and a bedtime story.

Personally, I'd like to see hanging make a comeback.

I'd probably take the firing squad (or the Chinese bullet to the back of the head) before relying on some buffoon of a doctor in Ohio to try to get a sedative dose right.

Comment Re:tl;dr no change except more outsourcing (Score 2) 359

And the intertwining of corporation and state increases.

Remember, libertarians: power will always find a vacuum. So there will always be strong government - the only thing we can influence is who controls the strings.

Really, this is just strong government period. The government is telling corporations they must store data for surveillance purposes. This is a tax, as business must pay for the storage. Big business might not mind it that much, because it increases barriers to entry for small guys and creates and incentive for the government to keep them in business.

I'd agree that totally removing a government creates a power vacuum. However, if Obama had made strict rules regarding a citizens privacy in regards to government and business that wouldn't create a power vacuum it would just mean the citizens are the empowered entity in the equation.

Comment Just a thought.. (Score 1) 380

Maybe some people aren't updating because new OS X features have been more annoying than helpful of late. Taking "Save As" out of textedit and creating a version control system was the point where I decided I'd wait out future upgrades until I had the time to read about what people were whining about with the new version.

Submission + - Massive Android Mobile Botnet Hijacking SMS Data (securityweek.com) 1

wiredmikey writes: A mobile botnet called MisoSMS is wreaking havoc on the Android platform, stealing personal SMS messages and exfiltrating them to attackers in China. Researchers at FireEye lifted the curtain off the threat on Monday, describing MisoSMS as "one of the largest advanced mobile botnets to date" and warning that it is being used in more than 60 spyware campaigns.

FireEye tracked the infections to Android devices in Korea and noted that the attackers are logging into command-and-controls in from Korea and mainland China, among other locations, to periodically read the stolen SMS messages. FireEye's research team discovered a total of 64 mobile botnet campaigns in the MisoSMS malware family and a command-and-control that comprises more than 450 unique malicious e-mail accounts.

Comment Re:Of course it could be big. (Score 4, Funny) 276

Bank of America is always looking for new ways to screw over their "customers", be it through fees, lying, or trying to steal their (paid off) houses through foreclosure (and blaming it on "computer error" when caught). They're probably drooling like hungry dogs over all the ways they can fleece people with Bitcoin...

That's what I found funny about the article. BofA thinks bitcoin could end up with "a reputation close to silver." and all I can think is "As opposed to Bank of America, which has a reputation close to shit, cancer, and child molesters."

Comment Re:Especially considering dirty bomb (Score 1) 98

Journalist keep touting the dirty bomb concept, but even with a big blast you would not propel enough Co 60 to kill people in a wide radius. There are study on this go look it up. The only reason such a bomb would be effective would be as a *psychological* tool. Since journalist and movie media keep touting the dirty bomb danger, it becomes one in the mind of people, and they would really panick if one was really set off.

I find that some people don't even understand the difference between a 'dirty' bomb and a conventional nuclear weapon. It's an effective scare tactic. Of course if the media wanted to go into the full freakout mode, they could bring up the hypothetical "cobalt bomb"

Comment Re:Already found (Score 1) 98

The unfortunate human who probably opened the container with the Cobalt-60 without proper protective gear however, is most likely no longer intact.

I was thinking the same thing. Can you picture the schmucks who hijacked this?

Criminal 1: Hey man, I wonder what we got? Maybe a truck full of ps4/Xbox one systems?
Criminal 2: (Opens box/removes shielding) Wait..what the f...is this?


On a more serious note, a former coworker works for a shipping company that is moving the xbox ones for Microsoft. There are a great deal of security measures on the trucks. Even though it's Mexico I'd expect they had some kind of security protocol if they were moving radioactive material.

Slashdot Top Deals

Remember to say hello to your bank teller.

Working...