I run Vista at home for my internet/gaming rig, UAC turned off, Aero turned off, on state of the art as of a year ago hardware, and everything seems peachy. I still despise Vista though.
/rant ON
Why do I despise Vista? Sometimes I have to support other people(family, friends, the guy down the hall whose work I depend on that doesn't have so good a relationship with IT). Why in the name of all that is Holy does microsoft have to screw around with things that work, that people know? Tell me, can you find the Mail widget in control panel using a 64bit version of Vista? It isn't on the "Main" screen of Control Panel where it f*cking should be. No, there is a "32bit Control Panel Widgets" button, buried in among all the other buttons, and you have to go there to find "Mail", what the f*ck? Why do they hide that? "Mail" is one of the Control Panel widgets that SHOULD BE ON THE MAIN PAGE!!111!!!!111!!! The first time I had to use it on 64 bit VISTA I looked like a complete idiot because I didn't anticipate that "Mail" shouldn't be on the main Control Panel page. Now I'm just pissed that I have to use an extra click to find it.
Why the F*CK did they do this crap, it is just like Office 2007, changing things that work for no F*CKING REASON. That is just one example of things being moved for no reason. I could go on, but I have already wasted enough of my time.
/rant OFF