Comment Re:Not vision (Score 1) 52
I am familiar with Nirenberg's work. What Nirenberg seems to be missing is that the programming outflow of the retina is altered in retinal disease. ON and OFF channels are substantially altered in retinal disease and the whole programming substrate is altered because the circuitry and programming down to the molecular levels is altered.
Its not all pessimism though as we will need to understand how the normal retina signals and I find her work to be interesting and compelling. Though she is not addressing *which channels* of information outflow are being encoded. There are 14-16 separate outflow channels in the retina that project to different areas of cortex and sub cortex and she is not addressing how to separate those channels and what those separate channels mean in terms of the "visual world".