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Comment False Positives and False Negatives (Score 4, Interesting) 106

I developed algorithms and code for a genetic testing company, mostly aimed at infectious diseases. But one day the FBI came calling to see if our system could be used for identifying people, seeing as it was 30-120minutes and fully automated. Spit on one side, get an answer on the other.

Sure, so I was briefly sent to the new alphabet-outreach department to look at that. And their test was based on matching 5 phenotypes out of 6. Worked well when it was first developed on 100 volunteers. In our test database of bit less than 200k subject samples, we'd get 0-10 positive matches for anyone in the lab, usually more than one. We'd also get false negatives, where we'd put someone's dna in the database and a new test would miss it. This is due to things like sample error, corruption, and genetic drift. Turns out the body is constantly evolving, and over 20 years blood genes are unlikely to match hair samples. In that 20 year span a hair sample may not match the previous one, due to drift.

I suggested they look at more than 6 phenotypes to improve accuracy, was told that's the standard and its not changing, and dropped from the team a few days later.

Comment How can a corporation commit a crime? (Score 1) 28

Or if it can, how can a living being commit a crime? What are these things?

For me, a crime means one being harming another. If a security guard steals my tootsie pop, it was not done by the imaginary corporation paying him in imaginary dollars. It was done by a dunce in a poorly fitting uniform. It was done physically, by a physical being, in the name of an imaginary being.

So I return to the original question: How can Tidal, a fictional corporation, face criminal charges? If found guilty will it be sent to jail? What is jail for a fiction? We are banned from thinking about it for a period? Who's in jail?

Comment been done before (Score 1) 37

My uncle Richard Fernsler came up with a method, late 1970s I recall, for identifying where lightning will strike, which helped launch his career as an exotic weapon developer for the Navy. His publications only hint at what actually gets built (functioning yet buggy unpredictable prototypes).
https://journals.ametsoc.org/d...

Comment Re:The problem is cost (Score 2) 73

Good summary of established technology, but cost is a red herring:
1) Moores Law may not be as fast for manufacturing, but it still holds that things get cheaper on repetition. Cars, TVs and computers all used to be luxury items for the well-off.
2) I've done a fair amount of coding for DNA/RNA analysis, and the resulting assays cost a few hundred dollars to run. A profitable $1000 test could be developed that IDs the cancer and describes the treatment in a few years time. An alternative to monoclonal antibodies is antisense drugs, which directly redirect/reprogram DNA of specific organs of the body. Antisense can be remarkably quick to produce, as the delivery package (retroviruses,etc.) are generic and there are various commercially available machines that mass-produce the genetic sequence of your choice. Isis Pharmaceuticals is one that's been working on antisense drugs for nearly 30 years, ten years ago I'd watch their R&D spit out a dozen possible drugs per day. Not hard to write D/RNA, not hard to read it, just need to bring those worlds together, along with a big database and proper analysis tools.
D/RNA looks just like software code, with start/end markers, execute statements, comments, etc. A rapid read-write interface is only a matter of time.

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