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How 1982's 'Blade Runner' Defined the Sci-Fi Film Genre (esquire.com) 101

Posted by EditorDavid from the remembering-replicants dept.
Esquire celebrates the 40th anniversary of the movie Blade Runner: Based on Philip K. Dick's 1968 novel Do Androids Dream Of Electric Sheep, Scott's film created a world so rich, so dirty and wet and worn out, so visually stunning, that imitation was an inevitability. Less gym-bro than The Terminator, less wacky than Terry Gilliam's Brazil, and less all-out apocalyptic than Mad Max, Blade Runner arguably defined not just 1980s science fiction, but in the forty years since its initial release, sci-fi films in general. From Ghost In The Shell, to Total Recall and Minority Report and even Black Panther, Blade Runner is owed a debt of gratitude.

Working from a formula he perfected in 1979's Alien, Scott brought his world of grimy industry and neon-lit shadows, rogue androids and put-upon protagonists to California, swapping Alien's body horror for the police procedural. Granted, Deckard isn't Ellen Ripley, but in its portrayal of the battered and bruised detective battling against the system, Blade Runner is a Chinatown of the future. That it was only Scott's third film as director makes it all the more impressive. (As an aside, has Harrison Ford's three film run of The Empire Strikes Back (1980), Raiders Of The Lost Ark (1981), and Blade Runner (1982) ever been beaten?).

Famously, the film was a critical and commercial flop in the U.S. with VHS sales and endless re-edits eventually leading to its cult status. (In 2004, it was even voted as the best science fiction film of all time by a panel of global scientists). Today, it's difficult to picture a sci-fi film that doesn't play homage. Would HBO's Westworld have updated its 1973 film version so successfully and stylishly without Blade Runner paving the way both visually and in terms of its musings on free will? And, decades before Elon Musk looked set to take over the world, Blade Runner's Tyrell Corporation (and indeed, Alien's Weyland-Yutani) was inspiring evil empires from Resident Evil's Umbrella Corporation to RoboCop's Omni Consumer Products and The Terminator's Cyberdyne Systems.
The article argues that Rutger Hauer's replicant character Roy Batty "delivers one of the greatest speeches in cinematic history in his 'Tears in rain' soliloquy."

And it points out that fans of Ridley Scott's prequels to Alien speculate those movies also exist in the same cinematic universe.

Comment Re: what about microchip compatibility (Score 1) 312

by bosef1 (#62153819) Attached to: Canada Considers Making Vaccines Mandatory

Oh man, I hadn't even thought about that. I know the FDA approved mixing shots, but a lot of that was still under emergency authorization, so who knows. We know how slow the FDA is on technology updates; look at all the issues there are with expensive hearing aids and user-unfriendly insulin pumps. And what happens when I get microchips on another carrier's network? Am I going to have to pay roaming charges? No one wants AT&T or Sprint microchips, I tell you what.
Medicine

Psilocybin Has No Short- Or Long-Term Detrimental Effects In Healthy People (kcl.ac.uk) 141

Posted by BeauHD from the promising-findings dept.
New research from the Institute of Psychiatry, Psychology, & Neuroscience (IoPPN) at King's College London, in partnership with COMPASS Pathways, has established that psilocybin can be safely administered at doses of either 10mg or 25mg to up to six participants simultaneously. King's College London reports: The research, published in The Journal of Psychopharmacology, is an essential first step in demonstrating the safety and feasibility of psilocybin -- a psychedelic drug isolated from the Psilocybe mushroom -- for use within controlled settings alongside talking therapy as a potential treatment for a range of mental health conditions, including treatment-resistant depression (TRD) and PTSD. Current treatment options for these conditions are ineffective or partially effective for many people, resulting in a significant unmet need. Early research has indicated a potential for psilocybin therapy to treat these groups, but no trials have been undertaken at the scale needed for regulatory approval to make the therapy available.

The trial is the first of its kind to thoroughly investigate the simultaneous administration of psilocybin. 89 healthy participants with no recent (within 1 year) use of psilocybin were recruited. 60 individuals were randomly picked to receive either a 10mg or 25mg dose of psilocybin in a controlled environment. In addition, all participants were provided with one-to-one support from trained psychotherapists. The remaining 29 participants acted as the control group and received a placebo, also with psychological support. Participants were closely monitored for six to eight hours following administration of psilocybin and then followed up for 12 weeks. During this time, they were assessed for a number of possible changes, including sustained attention, memory, and planning, as well as their ability to process emotions. Throughout the study, there were no instances of anyone withdrawing from the study due to an adverse event, and no consistent trends to suggest that either of the psilocybin doses had any short- or long-term detrimental effects on participants.

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