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+ - Play Jurassic Park with virtual DNA sequencer->

Submitted by nbauman
nbauman writes "Aipotu is free biology software that lets students manipulate and study the DNA of virtual organisms. They get an uncharacterized virtual plant, with different-colored flowers. They cross the plants to find the color alleles, learn the biochemical mechanism behind color formation, engineer a new color, and study the evolution of color. Windows, OS X, and Linux. from http://aipotu.umb.edu./

Each organism contains two DNA sequences, one from each parent. Students analyze DNA sequences to determine the phenotype, and scan for specific promoter and transcription terminator sequences. Pre-mRNA is scanned for splicing control sequences, spliced, and processed; open reading frames are translated. Structure of the protein is determined by an energy-minimization algorithm that uses ionic bonds, hydrogen bonds, and the hydrophobic effect to fold the protein on a two-dimensional hexagonal lattice. Software determines the function of the protein. Proteins with a specific shape can be colored, with particular amino acids in a critical region determining color.

One more thing. Case It! http://www.caseitproject.org/ lets you input DNA or protein sequences to generate Southern, Western, and dot blots, PCR, SNP microarrays, and ELISA.

These are 2 winners of the Inquiry-Based Instruction prize. More winners at http://www.sciencemag.org/site/special/ibi/"

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Play Jurassic Park with virtual DNA sequencer

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