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Lab Develops Artificial Womb
Posted by
michael
on Sun Feb 10, 2002 10:28 PM
from the barrayar dept.
from the barrayar dept.
Meowharishi writes: "According to this article at the Observer, scientists from Cornell University have successfully developed the first artificial womb. Embroys successfully attached themselves to the walls of these wombs and began to grow but were terminated to comply with regulations. Developments like this really offer tremendous opportunities for creating a family for those who cannot have children the old fashioned way."
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Lab Develops Artificial Womb
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Who else... (Score:4, Funny)
hrmm (Score:4, Funny)
You know, It always puzzled me. (Score:3, Insightful)
Why don't these researchers dedicate their energies to producing better contraceptives ?
We seem to live in a crazy world!
Re:You know, It always puzzled me. (Score:4, Insightful)
I very rarely get upset at 'flamebait'... (Score:5, Insightful)
'Overpopulated' is one of these wonderful terms, that suggests a scientific problem. But really means 'there are some people I would rather weren't born.'
More specifically, 'overpopulaton' - whatever that is supposed to mean - is used as a euphamism for 'too many of them, about the right number of us.'
When we talk of overpopulation, what we are really saying is 'there are a class of people who should not be allowed to reproduce.' That is a dangerous and evil thought...
Feel free to tell me I'm wrong!
*r
Don't get so worked up (Score:4, Insightful)
True. Some people think that population control means killing, if not sterilizing large amounts of people accordingly deemed unfit to reproduce. Or, failing that, strict fecundity restrictions a la China.
Most people who don't already have a genocidal streak inside them think more in terms of improved contraception and an increased standard of living [which need not be as profligate as that of your typical U.S. resident] as the ticket to a lower birth rate.
Happy, well-fed people with lives worth living tend to find it less of a priority to create new ones. That's what has been happening in almost every industrialized Western country in the past few decades, and is not happening in areas of greater human need.
Now, how to make this happen is another can of worms entirely---but most sane people concerned about overpopulation rightfully see authoritarian measures as a giant leap backward.
Pinky (Score:3, Funny)
I can see the Sci-fi scenarios now: Saddam Hussein breeding an army of clones to conquer the world.
Talk about Pinky and the Brain.
could this lead (Score:4, Interesting)
Bene Tleilax hiding in Cornell? (Score:3, Funny)
Daddy is also mummy? (Score:3, Interesting)
Re:survival of the weakest (Score:4, Funny)
I can think of advantages to all 3. Having a hard time coming up for a reason for ugly though.
Re:survival of the weakest (Score:5, Insightful)
Number one: I am deaf, it has NOTHING to do with my genes and I fully intend on procreating once I find a suitable life-partner to do so with.
Number two: If a couple, or woman, or man can take care of a child they should be permitted to procreate if they like. It's those who cannot take care of their offspring that should not be permitted to.
Number three: You assume that genes have everything to do with everything. My deafness is a far cry from being related to genetics, and so might peoples sterility, blindness, stupidity, and ugliness.
Number four: This is slashdot, I think we are all far beyond merely "depending" on technology. I can probably safely bet that 9/10ths of us would commit suicide if technology were eliminated from the planet tomorrow. (This is a safe bet because I'd probably be the first to go.)
There are enough LOGICAL reasons to argue against this without pushing buttons. ie:
1- Impact on the offspring-- The subtle shifting of hormonal balances, nutrients, etc. in the natural womb cannot be duplicated exactly. What will the impact on the offspring be mentally, physically, and emotionally?
2- Human bonding- The bonding process begins in the womb. We might end up with a whole generation of children who are emotionally and mentally like the monkey in the experiment with the wire and "fur" surrogate mothers.
3- Potential of mass-producing human life for slavery, medical experiments, or the like. Do we really want to open the doors to this possibility?
Screw evolution. Do you really think that anything going on today allows evolution? Miracle drugs and antibiotics to curb infection, breast implants to attract males, CPR to save lives, the internet to allow the meeting of geeks who would never otherwise venture outside even if it meant never reproducing... We're far beyond evolution at this point. Now all we can *really* do is sit back and watch the world fall apart or come together whatever the case might be.
-Sara
Re:This has all sorts of possibilities, bad and go (Score:4, Interesting)
Why ethical concerns? (Score:4, Interesting)
How is this different from a couple's child being gestated in a surrogate mother's womb?
How is this different from a different organ - the kidney - being replaced with external machinery (dialysis)?
How is this different from the prosthetic limbs or the artifical hearts in development?
Our bodies are imperfect and sometimes bits don't work properly or break. We have the means to workaround these shortcomings with technology; in this case, we still need parents to provide the genetic material and, obviously, raise the child once it is born.
Re:Why ethical concerns? (Score:5, Insightful)
It isn't, much, but there are a lot of people who have ethical concerns about that too. I won't argue those here (I actually am rather apathetic about the surrogate mother issue) but your first comment actually illustrates the point of those who hold the opposing view.
There is also the somewhat frightening idea of someone running amok with these things, and creating some sort of slave class of person to run things. read Brave New World. People were engineered to belong to different classes. More likely I see someplace using mass produced people as a menial labor force. It sounds like some sort of bad SciFi, but I can still see it happening.
At least using surrogate mothers requires someone else to go through 9 months of serious discomfort and moderate threat to life (as all childbirth does), making it far more difficult to do something like this.
How is this different from a different organ - the kidney - being replaced with external machinery (dialysis)?
Once again, it isn't, much. The problem is that dialysis is usually used in one of two situations.
Few people spend large amounts of their lives on dialysis. It can keep you alive, but is painful, unplesant, work intensive, and doesn't work as well as the real thing. If a kidney doesn't work as well, your health is poor. If a womb doesn't work as well, you could end up with all sorts of interesting physical and mental problems. In this instance we are not talking about preserving life, we are talking about creating it. There are ethical concers about dabbling with such things when we don't understand them.
How is this different from the prosthetic limbs or the artifical hearts in development?
It is many orders of magnitude more complex than prosthetic limbs or artificial hearts. The ethical concern comes from creating human life in this manner. Would it really be fair to create a life that society will have no choice but to institutionalize in some manner?
Our bodies are imperfect and sometimes bits don't work properly or break. We have the means to workaround these shortcomings with technology; in this case, we still need parents to provide the genetic material and, obviously, raise the child once it is born.
Yes we can work around some things, but an artifical heart, kidney or limb doesn't work quite as well as the original. There are inevitably problems. If someone needs a leg, they effect themselves. Creating a womb however also affects the life of the person being 'born?'.
The other problem (as I cited above) is that genetic material is extremely easy to obtain. It isn't particularly difficult to harvest eggs from women. This is done for invitrio(sp?) fertilization. For men, it is even easier, and we all know how it's done.
With just a little work it would be possible to create vast numbers of offspring. How these offspring would be used is one of the major ethical questions. Even in this century, there are countries that have no problem whatsoever with slavery. Would those same countries have a problem with creating some sort of easy labor force? OK, I honestly can't say I see China doing this. One of the reasons they have slavery relates to their overpopulation problem. This would compound it. Still it could be a fairly cheap and constant labor source.
All this aside, I really don't see it as too bad. The potential for abuse is great, but all technology can be abused in some manner. This could allow women who can not carry a child to term to have a child without the problems involved in using a surrogate (some of the legal complications alone are epic).
I would suggest strongly trying this with various animals and getting several completely normal animals (including primates) before ever attempting this on a human.
Even then, there will be legitimate ethical questions, but I leave most of those for someone else.
Abortion ethics? (Score:5, Interesting)
This device makes it possible for (baby|fetus)s to reach this "viability" mark much earlier...
I don't want to start a flame war, but what effect do you think technological advances such as these will have on ethics relating to unborn children/fetuses?
Ethical/legal/social implications (Score:3, Redundant)
Currently, abortion is legal until the fetus has reached a point of viability- that is, until it could conceivably live outside of its mother's womb on its own. Advances in medical science have been pushing that date back slowly since Roe v. Wade, but this is very big.
It's a pretty arbitrary line to begin with, and this makes it even farther from being grounded in modern science.
I'm not interested in having the yet another abortion debate, but I am curious how folks think this will change the rhetorical landscape for politicians, religous figures and ethicists. And, of course, for women.
Abortion replaced with transplation? (Score:4, Insightful)
However, there's another interesting consequence... What if a fetus could be transplated from a natural womb to an artificial one? Let's say a woman wants to have an abortion, and the doctor says, "We can either terminate the fetus, or we can transplant it to an artificial womb and put it up for adoption".
Would it ever be ethical to destroy the fetus in this case? This eliminates the argument of autonomy . Should a woman have the right to decide whether or not to destroy her fetus or simply put it up for adoption?
Better Idea (Score:3, Funny)
Or for creating an army of genetically enhanced flying monkeys. Fly my pretties, fly! Hahahahahaha!
Brave New World - Actual Text (Score:3, Interesting)
"I shall begin at the beginning," said the D.H.C. and the more zealous
students recorded his intention in their notebooks: Begin at the
beginning. "These," he waved his hand, "are the incubators." And opening
an insulated door he showed them racks upon racks of numbered test-tubes.
"The week's supply of ova. Kept," he explained, "at blood heat; whereas
the male gametes," and here he opened another door, "they have to be kept
at thirty-five instead of thirty-seven. Full blood heat sterilizes." Rams
wrapped in theremogene beget no lambs.
Still leaning against the incubators he gave them, while the pencils
scurried illegibly across the pages, a brief description of the modern
fertilizing process; spoke first, of course, of its surgical
introduction-"the operation undergone voluntarily for the good of Society,
not to mention the fact that it carries a bonus amounting to six months'
salary"; continued with some account of the technique for preserving the
excised ovary alive and actively developing; passed on to a consideration
of optimum temperature, salinity, viscosity; referred to the liquor in
which the detached and ripened eggs were kept; and, leading his charges to
the work tables, actually showed them how this liquor was drawn off from
the test-tubes; how it was let out drop by drop onto the specially warmed
slides of the microscopes; how the eggs which it contained were inspected
for abnormalities, counted and transferred to a porous receptacle; how
(and he now took them to watch the operation) this receptacle was immersed
in a warm bouillon containing free-swimming spermatozoa-at a minimum
concentration of one hundred thousand per cubic centimetre, he insisted;
and how, after ten minutes, the container was lifted out of the liquor and
its contents re-examined; how, if any of the eggs remained unfertilized,
it was again immersed, and, if necessary, yet again; how the fertilized
ova went back to the incubators; where the Alphas and Betas remained until
definitely bottled; while the Gammas, Deltas and Epsilons were brought out
again, after only thirty-six hours, to undergo Bokanovsky's Process.
"Bokanovsky's Process," repeated the Director, and the students underlined
the words in their little notebooks.
One egg, one embryo, one adult-normality. But a bokanovskified egg will
bud, will proliferate, will divide. From eight to ninety-six buds, and
every bud will grow into a perfectly formed embryo, and every embryo into
a full-sized adult. Making ninety-six human beings grow where only one
grew before. Progress.
"Essentially," the D.H.C. concluded, "bokanovskification consists of a
series of arrests of development. We check the normal growth and,
paradoxically enough, the egg responds by budding."
Responds by budding. The pencils were busy.
He pointed. On a very slowly moving band a rack-full of test-tubes was
entering a large metal box, another, rack-full was emerging. Machinery
faintly purred. It took eight minutes for the tubes to go through, he told
them. Eight minutes of hard X-rays being about as much as an egg can
stand. A few died; of the rest, the least susceptible divided into two;
most put out four buds; some eight; all were returned to the incubators,
where the buds began to develop; then, after two days, were suddenly
chilled, chilled and checked. Two, four, eight, the buds in their turn
budded; and having budded were dosed almost to death with alcohol;
consequently burgeoned again and having budded-bud out of bud out of
bud-were thereafter-further arrest being generally fatal-left to develop
in peace. By which time the original egg was in a fair way to becoming
anything from eight to ninety-six embryos- a prodigious improvement, you
will agree, on nature. Identical twins-but not in piddling twos and threes
as in the old viviparous days, when an egg would sometimes accidentally
divide; actually by dozens, by scores at a time.
"Scores," the Director repeated and flung out his arms, as though he were
distributing largesse. "Scores."
But one of the students was fool enough to ask where the advantage lay.
"My good boy!" The Director wheeled sharply round on him. "Can't you see?
Can't you see?" He raised a hand; his expression was solemn. "Bokanovsky's
Process is one of the major instruments of social stability!"
Major instruments of social stability.
Standard men and women; in uniform batches. The whole of a small factory
staffed with the products of a single bokanovskified egg.
"Ninety-six identical twins working ninety-six identical machines!" The
voice was almost tremulous with enthusiasm. "You really know where you
are. For the first time in history." He quoted the planetary motto.
"Community, Identity, Stability." Grand words. "If we could bokanovskify
indefinitely the whole problem would be solved."
Solved by standard Gammas, unvarying Deltas, uniform Epsilons. Millions of
identical twins. The principle of mass production at last applied to
biology.
Nine Months in a Sensory Deprivation Tank? (Score:5, Interesting)
What kind of psychological impact will it have if a baby is brought to term without any of the rocking, singing, ooh-ah, coo-coo, dinner, conversation, love and life of the mother in close contact? An "artificial womb" will presumably be a dark, enclosed tank with little or no human contact. There is substantial evidence to indicate that prenatal stimulation is important. I wonder what kind of messed up people will come out of these chambers.
Re:Nine Months in a Sensory Deprivation Tank? (Score:4, Insightful)
Embryology is 100% as complicated as all of human evolution. Every peice of genetic code is only functional in the context of the mother's womb.
Why nobody talks about adoption (Score:4, Informative)
What's up over there in the States? Is it rendered illegal to adopt a poor child from your local community or even a poor foreign country? Or is it unpopular now, because that cute little kiddie might have terrorist genes because it came from Somalia?
Speaking as an (adoptive) parent, there are a bunch of reasons.
Adoption works. It's truly sad that so few people understand that.
Just imagine!!! (Score:3, Funny)
She doesn't cook, she doesn't clean, but she will bear your children!
Successful my ass. (Score:3, Interesting)
It's not successful until the device can be proven to gestate a fetus to term, and that said fetus be functional and free of defencts (depending on the old truism of garbage in, garbage out with regards to the genetic materials). "Regulations" have allowed for nothing more than a proof of concept. Yee ha. Test it on a pig or something and see if it really works all the way.
Too many people are shooting straight from the hip with moral panic attacks about this- the results of which are essentially as close minded as "640k ought to be enough for anybody." The morally minded need to shut the fsck up and realize that they have no right to have ANY say in the procreation alternatives of other sentient individuals. I cannot assess wether or not this device is practical for reasons stated above- it's not a functional proof of concept until "regulations" (created or pushed through by the morally minded who seem to exist only to restrict the will of others) allow for a thorough test.
Is it a good idea? Of course; it's advancing science. Medical science and NASA would be about thirty years behind where we are now were it not for German scientific data garnered from the second world war.
The only life you have ANY say in is YOUR OWN. Now keep your mouth shut about why cloning and Gattica-style selective breeding is a bad idea.... because simply put, it doesn't presently exist, so we just don't KNOW, do we? It's not your life, it's not your choice, so fundamentally, it's *not your business* unless you're looking to reproduce and have run out of options.
There's a LOT more to it than that. (Score:5, Insightful)
Her body sacrifices the calcium in her bones, the energetic compounds and trace elements in her fat, and the vitamins in her bloodstream, handing it off to the foetus as directed by a plethora of signals. She gets morning sickness from folic acid deficiency and strange appetites at odd hours ("Honey, run out and get me some Ice Cream and Pickles!") whenever baby needs some oddball compound. And then there's the support, massage, and shaping performed by the bag of muscles the kid lives in for 9 months.
The signals are FAR from all known, and you can bet that kidlet will not form up healthy and happy if you just give him/her a stock nutrient solution rather than adjusting it according to his/her signals.
MOD PARENT UP! (Score:4, Insightful)
We have no idea what we're getting into. And we have no idea what we don't know yet about the natural gestation process.
It is a silly and frankly stupid notion that everyone has a right to reproduce biologically, and that that right must be enabled by expensive new technology. If you can't make a child naturally, you can adopt one. God knows there are enough already who need to be adopted.